Haemophilus influenzae: a forgotten cause of neonatal sepsis?

Acta Clin Belg. 2015 Jun;70(3):204-6. doi: 10.1179/2295333714Y.0000000104. Epub 2014 Dec 2.

Abstract

Due to the introduction of the conjugate vaccine against serotype b, neonatal sepsis caused by Haemophilus influenzae became very rare. There is little data in Belgium concerning the prevalence of H. influenzae early onset neonatal sepsis and articles about neonatal sepsis and H. influenzae published in the last decade are scarce. We report two invasive infections with a non-typeable H. influenzae. These cases show that neonatal sepsis caused by non-typeable H. influenzae may be underestimated and we believe that there is need for a better registration of this kind of infection.

Keywords: Early-onset neonatal sepsis,; Haemophilus influenzae,; Mors in utero,; Non-typeable Haemophilus influenzae.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Cefotaxime / administration & dosage*
  • Female
  • Haemophilus Infections* / drug therapy
  • Haemophilus Infections* / microbiology
  • Haemophilus Infections* / physiopathology
  • Haemophilus influenzae* / drug effects
  • Haemophilus influenzae* / immunology
  • Humans
  • Infant, Newborn
  • Microbial Sensitivity Tests
  • Sepsis* / drug therapy
  • Sepsis* / microbiology
  • Sepsis* / physiopathology
  • Serotyping / methods
  • Time Factors
  • Tobramycin / administration & dosage*
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Cefotaxime
  • Tobramycin