Acute liver failure following atorvastatin dose escalation: is there a threshold dose for idiosyncratic hepatotoxicity?

J Hepatol. 2015 Mar;62(3):751-2. doi: 10.1016/j.jhep.2014.11.019. Epub 2014 Nov 21.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged, 80 and over
  • Atorvastatin / administration & dosage
  • Atorvastatin / adverse effects*
  • Chemical and Drug Induced Liver Injury / etiology*
  • Chemical and Drug Induced Liver Injury / pathology
  • Female
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects*
  • Liver / drug effects
  • Liver / pathology
  • Liver Failure, Acute / chemically induced*
  • Liver Failure, Acute / pathology

Substances

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Atorvastatin