Analysis of incidence and genetic predisposition of preauricular sinus

Int J Pediatr Otorhinolaryngol. 2014 Dec;78(12):2255-7. doi: 10.1016/j.ijporl.2014.10.027. Epub 2014 Oct 25.

Abstract

Objectives: To evaluate the incidence of preauricular sinus, the association between preauricular sinus of a parent and their children, and the odds of hearing impairments in patients with preauricular sinus.

Methods: A cross-sectional study was performed using data from the Korea National Health and Nutrition Examination Survey. We evaluated data from 23,533 subjects who were interviewed between 2010 and 2012.

Results: The incidence of unilateral preauricular sinus was 1.3% and that of bilateral preauricular sinus was 0.3%. Female gender was statistically associated with preauricular sinus (adjusted odd ratio, AOR=1.401). There was no statistical difference between right- and left-sided preauricular sinus. There was an association between parents and their children for bilateral preauricular sinus (AOR of father's bilateral preauricular sinus=35.711; AOR of mother's bilateral preauricular sinus=7.683), but there was no association found for unilateral preauricular sinus. There was no link found between hearing impairment and preauricular sinus.

Conclusion: This large population-based study provides reliable information about the incidence of preauricular sinus, the association between preauricular sinus in parents and their children, and the lack of an association with hearing impairment; these results can help clinicians in the management of their patients.

Keywords: Auricle; Ear; Etiology; Fistula; Prevalence; Sinus.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Craniofacial Abnormalities / complications
  • Craniofacial Abnormalities / epidemiology*
  • Craniofacial Abnormalities / genetics*
  • Cross-Sectional Studies
  • Female
  • Genetic Predisposition to Disease*
  • Hearing Loss / epidemiology
  • Hearing Loss / etiology
  • Humans
  • Incidence
  • Infant
  • Male
  • Middle Aged
  • Parents
  • Pedigree
  • Republic of Korea / epidemiology
  • Sex Factors
  • Young Adult

Supplementary concepts

  • Preauricular Fistulae, Congenital