Adverse reactions to metal debris in metal-on-polyethylene total hip arthroplasty using a titanium-molybdenum-zirconium-iron alloy stem

J Arthroplasty. 2015 Feb;30(2):277-81. doi: 10.1016/j.arth.2014.06.030. Epub 2014 Oct 30.

Abstract

We report a series of three patients who underwent uncemented total hip arthroplasty with a modular titanium-molybdenum-zirconium-iron stem and a cobalt-chrome-molybdenum head on an ultra-high molecular weight highly cross-linked polyethylene liner bearing. All three cases subsequently developed pain and adverse reaction to metal debris, leading to revision of the implants within thirty-six months. They were subsequently found to have hypersensitivity to cobalt or chromium. However where tested, blood metal ion levels were within MHRA guideline limits. Corrosion was noted at the taper-trunnion junction. It is possible, that the multi alloy head-neck combination may lead to corrosion. Hypersensitivity to metal ions may result to ARMD at lower metal ion levels. The use of ceramic heads may help avoid this risk.

Keywords: adverse reaction to metal debris; corrosion; fretting; modular stem; total hip replacement.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Alloys
  • Arthroplasty, Replacement, Hip / adverse effects*
  • Arthroplasty, Replacement, Hip / instrumentation
  • Corrosion
  • Female
  • Hip Prosthesis / adverse effects*
  • Humans
  • Hypersensitivity / etiology
  • Ions / blood
  • Iron
  • Male
  • Metals / adverse effects*
  • Middle Aged
  • Osteoarthritis, Hip / surgery*
  • Polyethylene
  • Prosthesis Design
  • Prosthesis Failure
  • Vitallium / adverse effects*
  • Zirconium

Substances

  • Alloys
  • Ions
  • Metals
  • titanium molybdenum alloy
  • Vitallium
  • Polyethylene
  • Zirconium
  • Iron