Intraoperative red cell salvage during obstetric surgery in 50 Japanese women

Int J Gynaecol Obstet. 2015 Mar;128(3):256-9. doi: 10.1016/j.ijgo.2014.09.008. Epub 2014 Oct 24.

Abstract

Objective: To determine the clinical usefulness of intraoperative cell salvage (ICS) in obstetrics.

Methods: A retrospective analysis was performed using data for 50 patients who had received ICS blood during obstetric surgery at 13 Japanese facilities between January 1, 2007 and December 31, 2013. The frequencies of ICS-associated adverse events, allogeneic blood transfusion (ABT), and preoperative autologous donation (PAD) were assessed.

Results: Placenta previa was the indication for ICS in 42 (84%) women. The ICS blood was reinfused in all women (median 366 mL; range 80 to at least 3715). No ICS-associated adverse events occurred. The median estimated blood loss (EBL) was 2171 mL (range 574-47 000); 27 (54%) women lost at least 2000 mL. ABT was not used in 33 (66%) women. Among 26 women who lost at least 2000 mL of blood and were included in analyses, 12 (44%) did not receive ABT. EBL was linearly correlated with the total volume of transfused blood (P<0.001).

Conclusion: ICS caused no adverse events among women at elevated risk of peripartum hemorrhage and might be safe for use in obstetrics.

Keywords: Adverse events; Allogeneic blood transfusion; Amniotic fluid embolism; Autologous donation; Intraoperative cell salvage; Pregnancy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Loss, Surgical*
  • Erythrocyte Transfusion / adverse effects
  • Erythrocyte Transfusion / methods*
  • Female
  • Humans
  • Japan
  • Middle Aged
  • Obstetric Surgical Procedures / methods*
  • Operative Blood Salvage / adverse effects
  • Operative Blood Salvage / methods*
  • Placenta Previa / surgery
  • Pregnancy
  • Retrospective Studies
  • Young Adult