Robotic-assisted laparoscopic transanal total mesorectal excision for rectal cancer: a prospective pilot study

Dis Colon Rectum. 2015 Jan;58(1):145-53. doi: 10.1097/DCR.0000000000000265.

Abstract

Background: We performed a prospective pilot study of robotic-assisted laparoscopic transanal proctectomy with total mesorectal excision for the surgical treatment of rectal cancer. This study was to assess the feasibility and safety of robotic-assisted laparoscopic transanal total mesorectal excision.

Technique: All patients underwent robotic-assisted laparoscopic left colon mobilization, robotic-assisted laparoscopic transanal total mesorectal excision, ultralow mechanical colorectal or handsewn coloanal anastomosis, and a diverting loop ileostomy. Four patients with stage III disease received long-course preoperative chemoradiation before surgery.

Main outcome measures: Primary and secondary end points included the assessment of pathological examination and postoperative morbidity.

Results: Between August 2013 and January 2014, 4 men and 1 woman underwent robotic-assisted laparoscopic transanal total mesorectal excision. Patient age and BMI were 57 ± 13.9 years and 25.8 ± 2,7 kg/m. Tumors were located an average of 5 ± 1 cm from the anal verge and were preoperatively staged as T2N0M0 (1 patient) and T2N1M0 (4 patients). Mean operative time was 398 ± 88 minutes with no intraoperative complications. Mean length of hospital stay was 6 ± 1 days. A Clavien II, grade B anastomotic leakage developed in 1 patient postoperatively. In all cases, pathological examination of the total mesorectal excision specimens showed complete mesorectal excision with negative proximal, distal, and circumferential margins. All patients were disease-free at their initial 3-month follow-up.

Conclusions: Robotic-assisted laparoscopic transanal total mesorectal excision is a feasible and safe option for the surgical management of early-stage rectal cancers. Robotic technology with endowristed instruments and 3-dimensional high-definition imaging are of great help in overcoming the limitations of traditional laparoscopic transanal surgery. Long-term functional and oncological assessments of outcome are needed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Video-Audio Media

MeSH terms

  • Adenocarcinoma / pathology
  • Adenocarcinoma / surgery*
  • Anal Canal / surgery
  • Digestive System Surgical Procedures / methods*
  • Feasibility Studies
  • Female
  • Humans
  • Laparoscopy / methods*
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Pilot Projects
  • Prospective Studies
  • Rectal Neoplasms / pathology
  • Rectal Neoplasms / surgery*
  • Robotics*
  • Treatment Outcome