Seven-year clinical follow-up of a Chinese homozygous familial hypercholesterolemia child with premature xanthomas and coronary artery disease--a need for early diagnosis and aggressive treatment

Long Jiang; Feng Gao; Li-Bin Hu; Li-Yuan Sun; Xiao-Dong Pan; Jie Lin; Hai-Bo Zhang; Qiang Yong; Qian Wang; Ya Yang; Chun-Mei Wang; Shi-Wei Yang; Feng Zhang; Lu-Ya Wang

doi:10.1016/j.ijcard.2014.09.058

Seven-year clinical follow-up of a Chinese homozygous familial hypercholesterolemia child with premature xanthomas and coronary artery disease--a need for early diagnosis and aggressive treatment

Int J Cardiol. 2014 Nov 15;177(1):188-91. doi: 10.1016/j.ijcard.2014.09.058. Epub 2014 Sep 28.

Authors

Long Jiang¹, Feng Gao², Li-Bin Hu³, Li-Yuan Sun⁴, Xiao-Dong Pan⁴, Jie Lin⁴, Hai-Bo Zhang⁵, Qiang Yong⁶, Qian Wang⁶, Ya Yang⁶, Chun-Mei Wang⁷, Shi-Wei Yang⁴, Feng Zhang⁸, Lu-Ya Wang⁹

Affiliations

¹ Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, The Key Laboratory of Remodeling-related Cardiovascular Diseases, Ministry of Education, Department of Atherosclerosis, 2 Anzhen Road, ChaoYang District, Beijing 100029, China. Electronic address: [email protected].
² Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, The Key Laboratory of Remodeling-related Cardiovascular Diseases, Ministry of Education, Department of Atherosclerosis, 2 Anzhen Road, ChaoYang District, Beijing 100029, China. Electronic address: [email protected].
³ Department of Radiology, The China-Japan Friendship Hospital, Beijing 100029, China.
⁴ Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, The Key Laboratory of Remodeling-related Cardiovascular Diseases, Ministry of Education, Department of Atherosclerosis, 2 Anzhen Road, ChaoYang District, Beijing 100029, China.
⁵ Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, 2 Anzhen Road, Chaoyang District, Beijing 100029, China.
⁶ Department of Imaging, Beijing Anzhen Hospital, Capital Medical University, 2 Anzhen Road, Chaoyang District, Beijing 100029, China.
⁷ Department of Emergency, Beijing Anzhen Hospital, Capital Medical University, 2 Anzhen Road, Chaoyang District, Beijing 100029, China.
⁸ National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, Jilin, China; Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100029, China. Electronic address: [email protected].
⁹ Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, The Key Laboratory of Remodeling-related Cardiovascular Diseases, Ministry of Education, Department of Atherosclerosis, 2 Anzhen Road, ChaoYang District, Beijing 100029, China. Electronic address: [email protected].

PMID: 25499375
DOI: 10.1016/j.ijcard.2014.09.058

No abstract available

Keywords: Cardiovascular; Diagnosis; Familial hypercholesterolemia; Follow-up.

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Child
China
Coronary Artery Disease / complications*
Coronary Artery Disease / diagnosis
Diagnostic Imaging / methods*
Disease Management*
Early Diagnosis*
Follow-Up Studies
Homozygote
Humans
Hyperlipoproteinemia Type II / diagnosis*
Hyperlipoproteinemia Type II / genetics
Hyperlipoproteinemia Type II / therapy
Male
Pedigree
Time Factors
Xanthomatosis / complications*
Xanthomatosis / diagnosis