Hepatitis C virus genotype 7, a new genotype originating from central Africa

Donald G Murphy; Erwin Sablon; Jasmine Chamberland; Eric Fournier; Raymond Dandavino; Cécile L Tremblay

doi:10.1128/JCM.02831-14

Hepatitis C virus genotype 7, a new genotype originating from central Africa

J Clin Microbiol. 2015 Mar;53(3):967-72. doi: 10.1128/JCM.02831-14. Epub 2014 Dec 17.

Authors

Donald G Murphy¹, Erwin Sablon², Jasmine Chamberland³, Eric Fournier³, Raymond Dandavino⁴, Cécile L Tremblay³

Affiliations

¹ Laboratoire de Santé Publique du Québec, Institut National de Santé Publique du Québec, Sainte-Anne-de-Bellevue, Québec, Canada [email protected].
² Innogenetics NV, Ghent, Belgium.
³ Laboratoire de Santé Publique du Québec, Institut National de Santé Publique du Québec, Sainte-Anne-de-Bellevue, Québec, Canada.
⁴ Département de Néphrologie, Hôpital Maisonneuve-Rosemont, Montréal, Québec, Canada.

Abstract

We report a new hepatitis C virus (HCV) genotype identified in patients originating from the Democratic Republic of Congo. The prototype QC69 virus is shown to be a new lineage distinct from genotypes 1 to 6. Three additional patients were also found to be infected by a virus from this lineage, confirming its circulation in humans. We propose that these viruses be classified into HCV genotype 7.

Publication types

Case Reports

MeSH terms

Adolescent
Africa, Central / epidemiology
Cluster Analysis
Female
Genotype*
Hepacivirus / classification*
Hepacivirus / genetics*
Hepacivirus / isolation & purification
Hepatitis C / epidemiology
Hepatitis C / virology*
Humans
Male
Middle Aged
Molecular Sequence Data
Phylogeny
RNA, Viral / genetics
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid

Substances

RNA, Viral

Associated data

GENBANK/CS101285
GENBANK/CS101293
GENBANK/CS101294
GENBANK/CS101300
GENBANK/EF108306