Neurobrucellosis in children: Case series from Turkey

Pediatr Int. 2015 Aug;57(4):578-81. doi: 10.1111/ped.12510. Epub 2015 Feb 11.

Abstract

Background: Brucellosis is a multisystem disease that may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is an uncommon and serious complication of pediatric brucellosis.

Methods: We describe seven cases of neurobrucellosis.

Results: Ataxia (one patient), diplopia (one patient) and hearing loss (one patient) were among the neurological signs and symptoms. The most common diagnoses were acute meningitis and meningoencephalitis. Five of the patients fully recovered, one was lost to follow up and the other had hearing loss as a sequela.

Conclusion: Neurobrucellosis should be kept in mind in patients with any neurological or neuropsychiatric diseases who live in endemic areas of brucellosis.

Keywords: brucellosis; children; neurobrucellosis.

MeSH terms

  • Adolescent
  • Brucellosis / complications
  • Brucellosis / diagnosis
  • Brucellosis / epidemiology*
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Male
  • Meningoencephalitis / epidemiology*
  • Meningoencephalitis / etiology
  • Retrospective Studies
  • Tomography, X-Ray Computed
  • Turkey / epidemiology