De novo acute myeloid leukemia with monocytoid blasts and erythrophagocytosis

Clifford Blieden; Yao-Shan Fan; Jennifer Rose Chapman; Francisco Vega

doi:10.1002/ccr3.120

De novo acute myeloid leukemia with monocytoid blasts and erythrophagocytosis

Clin Case Rep. 2014 Dec;2(6):333-5. doi: 10.1002/ccr3.120. Epub 2014 Sep 15.

Authors

Clifford Blieden¹, Yao-Shan Fan², Jennifer Rose Chapman¹, Francisco Vega¹

Affiliations

¹ Division of Hematopathology, Department of Pathology and Laboratory Medicine, University of Miami/Sylvester Comprehensive Cancer Center Miami, Florida.
² Department of Cytogenetics, University of Miami/Sylvester Comprehensive Cancer Center Miami, Florida.

Abstract

Acute myeloid leukemia (AML) with t(8:16) is an infrequent acute leukemia subtype. It can occur de novo or more frequently therapy-related. The presence of blasts with monocytoid morphology and erythrophagocytosis suggest the presence of the t(8;16).

Keywords: AML with t(8;16); CREBBP; MYST3; erythrophagocytosis; monoblasts.