Right lower lobe autotransplantation for locally advanced central lung cancer

Yui Watanabe; Masami Sato; Yoshihiro Nakamura; Yasushi Hoshikawa; Aya Harada; Toshiyuki Nagata; Goichi Yotsumoto; Yutaka Imoto; Yoshinori Okada; Takashi Kondo

doi:10.1016/j.athoracsur.2014.02.065

Right lower lobe autotransplantation for locally advanced central lung cancer

Ann Thorac Surg. 2015 Jan;99(1):323-6. doi: 10.1016/j.athoracsur.2014.02.065.

Authors

Affiliations

¹ Department of General Thoracic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
² Department of General Thoracic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan. Electronic address: [email protected].
³ Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
⁴ Department of Cardiovascular and Gastroenterological Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

PMID: 25555957
DOI: 10.1016/j.athoracsur.2014.02.065

Abstract

A 44-year-old man with locally advanced central lung cancer was treated by right lower lobe lung autotransplantation after pneumonectomy using an extracellular phosphate-buffered solution for cold lung preservation. The advantage of the ex vivo operation made it possible to perform safe and definitive cancer resection without massive bleeding. Cold lung preservation brought some advantages, such as reducing the risk of ischemia-reperfusion injury compared with warm ischemia and allowing enough time to achieve microscopically negative margins. The patient returned to normal life with minimum loss of pulmonary reserve and no recurrence of lung cancer for 6 months.

Publication types

Case Reports

MeSH terms

Adenocarcinoma / pathology
Adenocarcinoma / surgery*
Adult
Humans
Lung Neoplasms / pathology
Lung Neoplasms / surgery*
Lung Transplantation*
Male
Neoplasm Staging
Transplantation, Autologous