Acute kidney injury in 2014: a step towards understanding mechanisms of renal repair

Azra Bihorac; John A Kellum

doi:10.1038/nrneph.2014.245

Acute kidney injury in 2014: a step towards understanding mechanisms of renal repair

Nat Rev Nephrol. 2015 Feb;11(2):74-5. doi: 10.1038/nrneph.2014.245. Epub 2015 Jan 6.

Authors

Azra Bihorac¹, John A Kellum²

Affiliations

¹ Department of Anaesthesiology, University of Florida, 1600 SW Archer Road, Medical Science Building Room M526B, Gainesville, FL 32610, USA.
² Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, School of Medicine, Room 604 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA.

Abstract

In 2014, key articles in the field of acute kidney injury highlighted the importance of tubular homeostasis in renal regeneration. Cell cycle regulators, inflammatory signals and progenitors were identified as important factors that mediate the balance between inflammation and tubular regeneration necessary for renal repair.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Acute Kidney Injury*
Humans
Kidney / physiology*
Regeneration*

Abstract

Publication types

MeSH terms

Grants and funding