Rickettsia buchneri sp. nov., a rickettsial endosymbiont of the blacklegged tick Ixodes scapularis

Int J Syst Evol Microbiol. 2015 Mar;65(Pt 3):965-970. doi: 10.1099/ijs.0.000047. Epub 2015 Jan 6.

Abstract

We obtained a rickettsial isolate from the ovaries of the blacklegged tick, Ixodes scapularis. The isolate (ISO7(T)) was grown in the Ixodes ricinus embryonic cell line IRE11. We characterized the isolate by transmission electron microscopy and gene sequencing. Phylogenetic analysis of 11 housekeeping genes demonstrated that the isolate fulfils the criteria to be classified as a representative of a novel rickettsial species closely related to 'Rickettsia monacensis'. These rickettsiae form a clade separate from other species of rickettsiae. Gene sequences indicated that several genes important in rickettsial motility, invasiveness and temperature adaptation were mutated (e.g. sca2, rickA, hsp22, pldA and htrA). We propose the name Rickettsia buchneri sp. nov. for this bacterium that infects the ovaries of the tick I. scapularis to acknowledge the pioneering contributions of Professor Paul Buchner (1886-1978) to research on bacterial symbionts. The type strain of R. buchneri sp. nov. is strain ISO-7(T) ( = DSM 29016(T) = ATCC VR-1814(T)).

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Bacterial Typing Techniques
  • DNA, Bacterial / genetics
  • Female
  • Genes, Bacterial
  • Ixodes / microbiology*
  • Microscopy, Electron, Transmission
  • Molecular Sequence Data
  • Ovary / microbiology
  • Phylogeny*
  • RNA, Ribosomal, 16S / genetics
  • Rickettsia / classification*
  • Rickettsia / genetics
  • Rickettsia / isolation & purification
  • Sequence Analysis, DNA
  • Symbiosis*

Substances

  • DNA, Bacterial
  • RNA, Ribosomal, 16S

Associated data

  • GENBANK/KDO02274
  • GENBANK/KDO02351
  • GENBANK/KDO02387
  • GENBANK/KDO02424
  • GENBANK/KDO02445
  • GENBANK/KDO02840
  • GENBANK/KDO02952
  • GENBANK/KDO02955
  • GENBANK/KDO03019
  • GENBANK/KDO03029
  • GENBANK/KDO03152
  • GENBANK/KDO03169
  • GENBANK/KDO03340
  • GENBANK/KDO03503
  • GENBANK/KDO03553
  • GENBANK/KDO03587
  • GENBANK/KDO03625