A novel Microchannel Electrode Array: towards bioelectronic medical interfacing of small peripheral nerves

Annu Int Conf IEEE Eng Med Biol Soc. 2014:2014:1981-4. doi: 10.1109/EMBC.2014.6944002.

Abstract

Bioelectronic medicine is an emerging field that relies on electrical signals to modulate complex neuronal circuits, particularly in the peripheral nervous system, as an alternative to drug-enabled therapeutics. Small autonomic nerves are one of the targets in this field, however, interfacing peripheral nerves smaller than 300 μm remains a challenge. Here we report the development of a Microchannel Electrode Array (DCEA) capable of interfacing nerve fascicles as small as 50-300μm. The current μCEA records and stimulates from 28 channels and is designed for easy implantation and removal, bearing promise to enable neural interfacing in BM.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Electrodes, Implanted*
  • Microelectrodes
  • Neural Prostheses*
  • Peripheral Nerves* / physiology
  • Peripheral Nerves* / surgery
  • Prosthesis Design
  • Rats
  • Rats, Sprague-Dawley