Assessment of mercury exposure among small-scale gold miners using mercury stable isotopes

Environ Res. 2015 Feb:137:226-34. doi: 10.1016/j.envres.2014.12.021. Epub 2015 Jan 8.

Abstract

Total mercury (Hg) concentrations in hair and urine are often used as biomarkers of exposure to fish-derived methylmercury (MeHg) and gaseous elemental Hg, respectively. We used Hg stable isotopes to assess the validity of these biomarkers among small-scale gold mining populations in Ghana and Indonesia. Urine from Ghanaian miners displayed similar Δ(199)Hg values to Hg derived from ore deposits (mean urine Δ(199)Hg=0.01‰, n=6). This suggests that urine total Hg concentrations accurately reflect exposure to inorganic Hg among this population. Hair samples from Ghanaian miners displayed low positive Δ(199)Hg values (0.23-0.55‰, n=6) and low percentages of total Hg as MeHg (7.6-29%, n=7). These data suggest that the majority of the Hg in these miners' hair samples is exogenously adsorbed inorganic Hg and not fish-derived MeHg. Hair samples from Indonesian gold miners who eat fish daily displayed a wider range of positive Δ(199)Hg values (0.21-1.32‰, n=5) and percentages of total Hg as MeHg (32-72%, n=4). This suggests that total Hg in the hair samples from Indonesian gold miners is likely a mixture of ingested fish MeHg and exogenously adsorbed inorganic Hg. Based on data from both populations, we suggest that total Hg concentrations in hair samples from small-scale gold miners likely overestimate exposure to MeHg from fish consumption.

Keywords: Biomarkers; Mercury isotopes; Methylmercury; Small-scale gold mining.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Biomarkers / analysis
  • Biomarkers / metabolism
  • Biomarkers / urine
  • Environmental Monitoring
  • Female
  • Fishes / metabolism*
  • Ghana
  • Hair / chemistry
  • Humans
  • Indonesia
  • Male
  • Mass Spectrometry
  • Mercury / analysis
  • Mercury / metabolism*
  • Mercury / urine
  • Mercury Isotopes / analysis
  • Mercury Isotopes / metabolism
  • Mercury Isotopes / urine
  • Methylmercury Compounds / analysis
  • Methylmercury Compounds / metabolism*
  • Methylmercury Compounds / urine
  • Middle Aged
  • Mining*
  • Occupational Exposure*
  • Soil Pollutants / analysis
  • Soil Pollutants / metabolism*
  • Soil Pollutants / urine
  • Young Adult

Substances

  • Biomarkers
  • Mercury Isotopes
  • Methylmercury Compounds
  • Soil Pollutants
  • Mercury