Predicting long-term outcomes of acute aortic dissection: a focus on gender

Expert Rev Cardiovasc Ther. 2015 Mar;13(3):325-31. doi: 10.1586/14779072.2015.1004313. Epub 2015 Jan 21.

Abstract

Acute aortic disease ranks as the 19th leading cause of death with steadily increasing incidence. The prevalence of aneurysms varies depending on the localization along the aorta with a mortality of aortic rupture of around 80%. Traditionally, aortic disease affects men more frequently than women, however, with a varying gender ratio. Nevertheless, in the setting of acute aortic dissection, the International Registry of Acute Aortic Dissections identified significant gender-related differences in the management of both sexes with acute aortic conditions. Current data suggest that women are at an increased risk of both dying from aortic dissection and having aorta-related complications than men. This review aims to report on current evidence of gender impact on natural history, treatment and outcomes in patients with acute aortic dissection.

Keywords: TAA; aortic dissection; gender; outcome; thoracic endovascular stent-graft repair.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Animals
  • Aortic Aneurysm / epidemiology*
  • Aortic Aneurysm / mortality
  • Aortic Aneurysm / therapy
  • Aortic Dissection / epidemiology*
  • Aortic Dissection / mortality
  • Aortic Dissection / therapy
  • Female
  • Healthcare Disparities / statistics & numerical data*
  • Humans
  • Incidence
  • Male
  • Outcome Assessment, Health Care
  • Prevalence
  • Sex Factors
  • Time Factors