Comparison of Risk Scores for Prediction of Complications following Aortic Valve Replacement

Heart Lung Circ. 2015 Jun;24(6):595-601. doi: 10.1016/j.hlc.2014.11.021. Epub 2014 Dec 12.

Abstract

Background: Risk models play an important role in stratification of patients for cardiac surgery, but their prognostic utilities for post-operative complications are rarely studied. We compared the EuroSCORE, EuroSCORE II, Society of Thoracic Surgeon's (STS) Score and an Australasian model (Aus-AVR Score) for predicting morbidities after aortic valve replacement (AVR), and also evaluated seven STS complications models in this context.

Methods: We retrospectively calculated risk scores for 620 consecutive patients undergoing isolated AVR at Auckland City Hospital during 2005-2012, assessing their discrimination and calibration for post-operative complications.

Results: Amongst mortality scores, the EuroSCORE was the best at discriminating stroke (c-statistic 0.845); the EuroSCORE II at deep sternal wound infection (c=0.748); and the STS Score at composite morbidity or mortality (c=0.666), renal failure (c=0.634), ventilation>24 hours (c=0.732), return to theatre (c=0.577) and prolonged hospital stay >14 days post-operatively (c=0.707). The individual STS complications models had a marginally higher c-statistic (c=0.634-0.846) for all complications except mediastinitis, and had good calibration (Hosmer-Lemeshow test P-value 0.123-0.915) for all complications.

Conclusion: The STS Score was best overall at discriminating post-operative complications and their composite for AVR. All STS complications models except for deep sternal wound infection had good discrimination and calibration for post-operative complications.

Keywords: Aortic stenosis; Aortic valve replacement; Cardiac surgery complications; Risk score; Valve surgery.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Analysis of Variance
  • Aortic Valve Stenosis / diagnostic imaging
  • Aortic Valve Stenosis / mortality*
  • Aortic Valve Stenosis / surgery*
  • Cohort Studies
  • Echocardiography, Doppler
  • Female
  • Follow-Up Studies
  • Heart Valve Prosthesis
  • Heart Valve Prosthesis Implantation / methods*
  • Heart Valve Prosthesis Implantation / mortality
  • Hospital Mortality / trends*
  • Humans
  • Length of Stay
  • Male
  • Middle Aged
  • New Zealand
  • Postoperative Complications / mortality
  • Postoperative Complications / physiopathology
  • Predictive Value of Tests
  • ROC Curve
  • Retrospective Studies
  • Risk Assessment
  • Severity of Illness Index
  • Statistics, Nonparametric
  • Survival Rate
  • Treatment Outcome