Effects of verapamil on tardive dyskinesia and psychosis in schizophrenic patients

J Clin Psychiatry. 1989 Jan;50(1):26-7.

Abstract

Nine hospitalized schizophrenic patients with tardive dyskinesia were treated with the calcium-channel antagonist verapamil under single-blind conditions. The tardive dyskinesia and activation scores decreased, and the anxiety/depression scores increased. The changes were small but statistically significant.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Antipsychotic Agents / adverse effects
  • Anxiety Disorders / psychology
  • Depressive Disorder / psychology
  • Dyskinesia, Drug-Induced / drug therapy*
  • Dyskinesia, Drug-Induced / etiology
  • Dyskinesia, Drug-Induced / psychology
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Psychiatric Status Rating Scales
  • Schizophrenia / drug therapy*
  • Schizophrenic Psychology*
  • Verapamil / therapeutic use*

Substances

  • Antipsychotic Agents
  • Verapamil