Reliability and validity of active-seated: An outcome in dystrophinopathy

Muscle Nerve. 2015 Sep;52(3):356-62. doi: 10.1002/mus.24557. Epub 2015 Jul 2.

Abstract

Introduction: Traditional upper extremity measures typically focus on distal abilities and do not quantify the unique progression of decline in dystrophinopathy. We designed ACTIVE-seated to meet this need. Our objective was to establish the tool's validity and reliability.

Methods: ACTIVE-seated uses the Microsoft Kinect gaming interface to quantify functional reaching ability while playing a custom-designed game. A skeletal tracking algorithm was used to determine the furthest arm excursion in all planes in 61 subjects with dystrophinopathy and 16 controls.

Results: Total reachable area was scaled based on arm length to standardize comparisons across subjects and accommodate growth. ACTIVE-seated discriminately ranked subjects from normal controls and by Brooke level (P < 0.001). Scores were highly correlated with parent reports of daily activities and mobility (P < 0.05). Test-retest reliability of ACTIVE-seated was excellent (ICC = 0.97, P < 0.0001).

Conclusions: Initial evaluation of reliability and validity suggests that ACTIVE-seated shows promise as a clinical and research outcome for individuals with dystrophinopathy.

Keywords: Kinect; muscular dystrophy; outcome assessment; reach volume; upper extremity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living*
  • Adolescent
  • Adult
  • Algorithms*
  • Case-Control Studies
  • Child
  • Computer Peripherals*
  • Humans
  • Male
  • Mobility Limitation*
  • Muscular Dystrophy, Duchenne / physiopathology*
  • Reproducibility of Results
  • Upper Extremity / physiopathology*
  • Video Games*
  • Young Adult