Inhibition of epoxide hydrolase by anticonvulsants and risk of teratogenicity

Lancet. 1989 Mar 18;1(8638):610-1. doi: 10.1016/s0140-6736(89)91630-9.
No abstract available

Publication types

  • Letter

MeSH terms

  • Abnormalities, Drug-Induced / etiology
  • Anticonvulsants / adverse effects*
  • Drug Interactions
  • Epoxide Hydrolases / antagonists & inhibitors*
  • Female
  • Humans
  • Infant, Newborn
  • Microsomes, Liver / enzymology
  • Pregnancy
  • Valproic Acid / adverse effects
  • Valproic Acid / analogs & derivatives

Substances

  • Anticonvulsants
  • Valproic Acid
  • Epoxide Hydrolases
  • dipropylacetamide