Recurrence of disseminated Mycobacterium avium complex disease in a patient with anti-gamma interferon autoantibodies by reinfection

J Clin Microbiol. 2015 Apr;53(4):1436-8. doi: 10.1128/JCM.03339-14. Epub 2015 Feb 4.

Abstract

We report a case of recurrent disseminated Mycobacterium avium complex (DMAC) disease with anti-gamma interferon autoantibodies. To our knowledge, this is the first reported case caused by reinfection with a separate isolate of M. avium. DMAC disease activity was monitored using serum IgG antibody titers against lipid antigens extracted from a MAC strain.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Autoantibodies / immunology*
  • Female
  • Humans
  • Interferon-gamma / immunology*
  • Mycobacterium avium Complex*
  • Mycobacterium avium-intracellulare Infection / immunology*
  • Mycobacterium avium-intracellulare Infection / microbiology*

Substances

  • Autoantibodies
  • Interferon-gamma