Prolonged Q-T interval following astemizole overdose

Arch Emerg Med. 1989 Mar;6(1):63-5. doi: 10.1136/emj.6.1.63.

Abstract

Astemizole overdose has been reported to cause torsades-de-pointes and in the present case it caused prolongation of the Q-T interval. Astemizole overdoses should be managed in a similar way to overdose with other cardiotoxic drugs.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adolescent
  • Astemizole
  • Benzimidazoles / poisoning*
  • Electrocardiography
  • Female
  • Histamine H1 Antagonists / poisoning*
  • Humans
  • Tachycardia, Sinus / chemically induced*
  • Tachycardia, Supraventricular / chemically induced*

Substances

  • Benzimidazoles
  • Histamine H1 Antagonists
  • Astemizole