Photochemical synthesis of biocompatible and antibacterial silver nanoparticles embedded within polyurethane polymers

Photochem Photobiol Sci. 2015 Apr;14(4):661-4. doi: 10.1039/c4pp00404c.

Abstract

In situ light initiated synthesis of silver nanoparticles (AgNP) was employed for AgNP incorporation within the polymeric matrices of medical grade polyurethane. The resulting materials showed improved antibacterial and antibiofilm activity against Pseudomonas aeruginosa with negligible toxicity for human primary skin cells and erythrocytes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemical synthesis*
  • Anti-Bacterial Agents / chemistry
  • Biocompatible Materials / chemical synthesis*
  • Biocompatible Materials / chemistry
  • Cell Count
  • Cell Survival / drug effects
  • Cells, Cultured
  • Erythrocytes / chemistry
  • Fibroblasts / drug effects
  • Humans
  • Metal Nanoparticles / chemistry*
  • Microscopy, Electron, Scanning
  • Photochemical Processes*
  • Polyurethanes / chemical synthesis*
  • Polyurethanes / chemistry
  • Pseudomonas aeruginosa / drug effects
  • Silver Compounds / chemical synthesis*
  • Silver Compounds / chemistry
  • Skin / drug effects
  • Spectrum Analysis

Substances

  • Anti-Bacterial Agents
  • Biocompatible Materials
  • Polyurethanes
  • Silver Compounds