Stentless porcine bioprosthesis in pulmonary position after ross procedure: midterm results

Ann Thorac Surg. 2015 Apr;99(4):1255-9. doi: 10.1016/j.athoracsur.2014.10.033. Epub 2015 Feb 3.

Abstract

Background: Stentless porcine roots (SPV) have been proposed for right ventricular outflow tract reconstruction in the Ross procedure due to the relative availability of pulmonary homografts in large diameters. We report here our experience with SPV used in the Ross procedure.

Methods: Between March 1992 and February 2011, 360 patients had a Ross procedure; 61 patients received a SPV in pulmonary position and they represent the study population. Mean age was 38 ± 7.6 years. Indication for surgery was an infective endocarditis in 15 cases, there were 3 redo operations. Median SPV diameter was 29 mm (range, 25 to 29 mm). Pulmonary stenosis was defined as a peak transvalvular gradient of more than 50 mm Hg.

Results: Perioperative mortality was 4.9% (3 patients) and late mortality was 3.3% (2 patients). Median follow-up was 4 years (range, 7 days to 14.9 years). There was no reoperation on the right ventricle outflow tract, and freedom from pulmonary stenosis was 100% at 5 years. Mean transpulmonary gradients were 7.1 ± 3.1 mm Hg and 13.5 ± 6.8 mm Hg postoperatively and at 5 years, respectively. Mean transpulmonary gradient increased faster over time when the SPV diameter was less than 29 mm (p = 0.03).

Conclusions: The SPV could represent an alternative to cryopreserved pulmonary homografts during the Ross procedure in adult patients. Hemodynamic results were improved by using large diameter SPV, but longer follow-up is mandatory to confirm those results.

Publication types

  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Bioprosthesis*
  • Cardiac Surgical Procedures / adverse effects
  • Cardiac Surgical Procedures / methods
  • Cohort Studies
  • Combined Modality Therapy
  • Echocardiography, Doppler / methods
  • Female
  • Follow-Up Studies
  • Heart Valve Prosthesis Implantation / methods*
  • Heart Valve Prosthesis Implantation / mortality
  • Heart Valve Prosthesis*
  • Humans
  • Male
  • Middle Aged
  • Prosthesis Design*
  • Prosthesis Failure
  • Pulmonary Valve Stenosis / diagnostic imaging
  • Pulmonary Valve Stenosis / mortality
  • Pulmonary Valve Stenosis / surgery*
  • Retrospective Studies
  • Stents
  • Survival Rate
  • Swine
  • Time Factors
  • Treatment Outcome
  • Ventricular Outflow Obstruction / diagnostic imaging
  • Ventricular Outflow Obstruction / surgery
  • Young Adult