Treatment of refractory simple partial status epilepticus by the addition of oral lacosamide in neurosurgical patients. Report of 3 cases

Georgios F Hadjigeorgiou; Adamantios Petsanas; Christos Anagnostopoulos; Christos Chamilos; Georgios Vranos; Philokypros Spyridakis

doi:10.1016/j.ebcr.2013.03.005

Treatment of refractory simple partial status epilepticus by the addition of oral lacosamide in neurosurgical patients. Report of 3 cases

Epilepsy Behav Case Rep. 2013 May 4:1:69-70. doi: 10.1016/j.ebcr.2013.03.005. eCollection 2013.

Authors

Georgios F Hadjigeorgiou¹, Adamantios Petsanas², Christos Anagnostopoulos², Christos Chamilos², Georgios Vranos², Philokypros Spyridakis²

Affiliations

¹ Department of Neurosurgery, Red Cross Hospital, 1 Athanasaki St., 11526 Athens, Greece ; Department of Neurosurgery, Tzanio General Hospital, 1 Zani & Afentouli St., 18536 Piraeus, Athens, Greece.
² Department of Neurosurgery, Tzanio General Hospital, 1 Zani & Afentouli St., 18536 Piraeus, Athens, Greece.

Abstract

Lacosamide is a new antiepileptic drug that has been successfully used for the treatment of partial seizures. We report three neurosurgical cases of simple partial status epilepticus refractory to multiple antiepileptic medications. The addition of oral lacosamide in doses of 200-400 mg in combination with the existing treatment had successfully controlled the seizures within four days.

Keywords: Antiepileptic drug; Lacosamide; Seizure; Status epilepticus; Treatment.