Web of the extended Myc network captures metabolism for tumorigenesis

Chi V Dang

doi:10.1016/j.ccell.2015.01.004

Web of the extended Myc network captures metabolism for tumorigenesis

Cancer Cell. 2015 Feb 9;27(2):160-2. doi: 10.1016/j.ccell.2015.01.004.

Author

Chi V Dang¹

Affiliation

¹ Abramson Cancer Center, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: [email protected].

PMID: 25670077
DOI: 10.1016/j.ccell.2015.01.004

Abstract

In this issue of Cancer Cell, Carroll and colleagues describe the role of MondoA, a member of the Myc-Max-Mxd-Mxl transcription factor network (termed the extended Myc network herein), in Myc-mediated alterations in cancer cell metabolism and tumorigenesis.

Publication types

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MeSH terms

Animals
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / genetics*
Humans
Neuroblastoma / genetics*
Proto-Oncogene Proteins c-myc / genetics*

Substances

Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
MLXIP protein, human
MYC protein, human
Proto-Oncogene Proteins c-myc