Survey on current practices for neurological prognostication after cardiac arrest

Resuscitation. 2015 May:90:158-62. doi: 10.1016/j.resuscitation.2015.01.018. Epub 2015 Feb 9.

Abstract

Purpose: To investigate current practices and timing of neurological prognostication in comatose cardiac arrest patients.

Methods: An anonymous questionnaire was distributed to the 8000 members of the European Society of Intensive Care Medicine during September and October 2012. The survey had 27 questions divided into three categories: background data, clinical data, decision-making and consequences.

Results: A total of 1025 respondents (13%) answered the survey with complete forms in more than 90%. Twenty per cent of respondents practiced outside of Europe. Overall, 22% answered that they had national recommendations, with the highest percentage in the Netherlands (>80%). Eighty-nine per cent used induced hypothermia (32-34 °C) for comatose cardiac arrest patients, while 11% did not. Twenty per cent had separate prognostication protocols for hypothermia patients. Seventy-nine per cent recognized that neurological examination alone is not enough to predict outcome and a similar number (76%) used additional methods. Intermittent electroencephalography (EEG), brain computed tomography (CT) scan and evoked potentials (EP) were considered most useful. Poor prognosis was defined as cerebral performance category (CPC) 3-5 (58%) or CPC 4-5 (39%) or other (3%). When prognosis was considered poor, 73% would actively withdraw intensive care while 20% would not and 7% were uncertain.

Conclusion: National recommendations for neurological prognostication after cardiac arrest are uncommon and only one physician out of five uses a separate protocol for hypothermia treated patients. A neurological examination alone was considered insufficient to predict outcome in comatose patients and most respondents advocated a multimodal approach: EEG, brain CT and EP were considered most useful. Uncertainty regarding neurological prognostication and decisions on level of care was substantial.

Keywords: Cardiac arrest; Coma; Outcome; Prognostication; Survey.

MeSH terms

  • Brain / diagnostic imaging
  • Brain Diseases / diagnosis
  • Brain Diseases / etiology*
  • Clinical Decision-Making
  • Coma / therapy
  • Electroencephalography
  • Europe
  • Evoked Potentials
  • Heart Arrest / complications*
  • Heart Arrest / therapy
  • Humans
  • Hypothermia, Induced / statistics & numerical data
  • Neurologic Examination
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Prognosis
  • Societies, Medical
  • Surveys and Questionnaires
  • Tomography, X-Ray Computed
  • Withholding Treatment / statistics & numerical data