A novel mutation in ICOS presenting as hypogammaglobulinemia with susceptibility to opportunistic pathogens

J Allergy Clin Immunol. 2015 Sep;136(3):794-797.e1. doi: 10.1016/j.jaci.2014.12.1940. Epub 2015 Feb 10.
No abstract available

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Agammaglobulinemia / complications
  • Agammaglobulinemia / genetics*
  • Agammaglobulinemia / immunology
  • Agammaglobulinemia / therapy
  • Child, Preschool
  • Colitis / complications
  • Colitis / genetics*
  • Colitis / immunology
  • Colitis / therapy
  • Gene Expression
  • Genetic Predisposition to Disease
  • Hematopoietic Stem Cell Transplantation
  • Humans
  • Inducible T-Cell Co-Stimulator Protein / genetics*
  • Inducible T-Cell Co-Stimulator Protein / immunology
  • Lymphocyte Activation
  • Male
  • Mutation
  • Opportunistic Infections / complications
  • Opportunistic Infections / genetics*
  • Opportunistic Infections / immunology
  • Opportunistic Infections / therapy
  • T-Lymphocytes / immunology*
  • T-Lymphocytes / pathology

Substances

  • ICOS protein, human
  • Inducible T-Cell Co-Stimulator Protein