Determining Health-Related Quality-of-Life Outcomes Using the SF-6D Preference-Based Measure in Patients Following Total Knee Arthroplasty

J Arthroplasty. 2015 Jul;30(7):1150-3. doi: 10.1016/j.arth.2015.01.050. Epub 2015 Feb 7.

Abstract

The SF-6D, a health-related quality-of-life measure, assigns value to patients' perception of their health. We determined SF-6D values of 844 TKA patients, deduced clinical relevance of value changes using effect size, and compared these to clinical and functional improvements 6weeks, 3months, and 1 through 5years post-operatively. The SF-6D significantly improved at all follow-ups after 6weeks. The effect size indicated clinical relevance at every follow-up. The KSS improved at all follow-ups (+43, +51, +56, +57, +57 points), and LEAS scores improved at follow-ups after 6weeks (+1 point at 3months, +2 points thereafter), correlating with SF-6D changes. Deducing utility scores facilitates cost analyses, allowing clinicians to deduce quality-adjusted life-years and economic impacts of treatments.

Keywords: SF-6D; health-related measure; outcomes; quality of life; total knee arthroplasty.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Arthroplasty, Replacement, Knee* / economics
  • Body Mass Index
  • Databases, Factual
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Osteoarthritis, Knee / economics
  • Osteoarthritis, Knee / psychology*
  • Patient Preference*
  • Postoperative Period
  • Quality of Life*
  • Quality-Adjusted Life Years*
  • Surveys and Questionnaires
  • Treatment Outcome