Neoadjuvant denosumab for extensive giant cell tumor in os ischium: a case report

Acta Orthop. 2015 Jun;86(3):393-5. doi: 10.3109/17453674.2014.1002345. Epub 2015 Feb 14.

Authors

Lizz van der Heijden¹, Michiel A J van de Sande, Pancras C W Hogendoorn, Hans Gelderblom, P D Sander Dijkstra

Affiliation

¹ Departments of Orthopedic Surgery , Leiden University Medical Center, Leiden , the Netherlands.

No abstract available

Publication types

Case Reports

MeSH terms

Antibodies, Monoclonal / therapeutic use*
Antibodies, Monoclonal, Humanized / therapeutic use*
Bone Neoplasms / diagnostic imaging
Bone Neoplasms / pathology
Bone Neoplasms / therapy*
Combined Modality Therapy
Denosumab
Giant Cell Tumor of Bone / diagnostic imaging
Giant Cell Tumor of Bone / pathology
Giant Cell Tumor of Bone / therapy*
Humans
Ischium* / diagnostic imaging
Ischium* / pathology
Ischium* / surgery
Magnetic Resonance Imaging
Male
Middle Aged
Neoadjuvant Therapy
Osteotomy
RANK Ligand / antagonists & inhibitors*
Tomography, X-Ray Computed
Treatment Outcome

Substances

Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
RANK Ligand
TNFSF11 protein, human
Denosumab

Associated data

ClinicalTrials.gov/NCT00680992