Impaired DNA synthesis by early pubertal cryptorchid testis in vitro

M Nakamura; N Nonomura; M Namiki; A Okuyama; E Koh; N Kondoh; M Takeyama; H Fujioka; H Kiyohara; Y Nishimune

doi:10.3109/01485018908986763

Impaired DNA synthesis by early pubertal cryptorchid testis in vitro

Arch Androl. 1989;22(2):137-41. doi: 10.3109/01485018908986763.

Authors

M Nakamura¹, N Nonomura, M Namiki, A Okuyama, E Koh, N Kondoh, M Takeyama, H Fujioka, H Kiyohara, Y Nishimune, et al.

Affiliation

¹ Department of Urology, School of Medicine, Osaka University, Japan.

PMID: 2568822
DOI: 10.3109/01485018908986763

Abstract

To study the spermatogenic potential of the early pubertal cryptorchid testis, testicular DNA synthesis was examined in vitro. DNA synthesis by early pubertal cryptorchid testis was inhibited and lost its normal temperature sensitivity. The spermatogenic potential of the cryptorchid testis may be impaired as early as puberty.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cryptorchidism / metabolism*
Culture Techniques
DNA / biosynthesis*
Humans
Male
Puberty*
Spermatogenesis
Temperature
Testis / metabolism*

Substances

DNA