Poor glycemic control in type 2 diabetes in the South of the Sahara: the issue of limited access to an HbA1c test

Diabetes Res Clin Pract. 2015 Apr;108(1):187-92. doi: 10.1016/j.diabres.2014.08.025. Epub 2014 Sep 16.

Abstract

Background: Management of type 2 diabetes remains a challenge in Africa. The objective of this study was to evaluate the prevalence and predictors of poor glycemic control in patients with type 2 diabetes living in sub-Saharan.

Patients and methods: This was a cross-sectional study involving 1267 people (61% women) with type 2 diabetes (mean age 58 years) recruited across health facilities in Cameroon and Guinea. Predictors of poor glycemic control (HbA1c ≥7.0% (53 mmol/mol)) were investigated via logistic regressions.

Results: The mean body mass index was 27.4 ± 5.8 kg/m(2), and 74% of patients had poor glycemic control. Predictors of poor glycemic control in multivariable regression models were recruitment in Guinea [odd ratio: 2.91 (95% confidence interval 2.07 to 4.11)], age <65 years [1.40 (1.04 to 1.88)], diabetes duration ≥3 years [2.36 (1.74 to 3.21)], treatment with: oral glucose control agents [3.46 (2.28 to 5.26)], insulin alone or with oral glucose control agents [7.74 (4.70 to 12.74)] and absence of a previous HbA1c measurement in Guinea [2.96 (1.30 to 6.75)].

Conclusion: Poor control of blood glucose is common in patients with type 2 diabetes in these two countries. Limited access to HbA1c appears to be a key factor associated with poor glycemic control in Guinea, and should be addressed by health policies targeting improvement in the outcomes of diabetes care.

Keywords: Glycemic control; Sub-Saharan Africa; Type 2 diabetes.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Glucose / analysis*
  • Blood Glucose Self-Monitoring / methods*
  • Body Mass Index
  • Cameroon / epidemiology
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / blood*
  • Diabetes Mellitus, Type 2 / epidemiology
  • Female
  • Glycated Hemoglobin / analysis*
  • Guinea / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Odds Ratio
  • Prevalence
  • Retrospective Studies

Substances

  • Blood Glucose
  • Glycated Hemoglobin A