Cutaneous leukocytoclastic vasculitis associated with anti-tuberculosis drugs

Pediatr Int. 2015;57(1):155-7. doi: 10.1111/ped.12403.

Abstract

Leukocytoclastic vasculitis (LCV), a disease characterized by inflammation of the small vessels, presents with palpable purpura, especially in the lower extremities. Its etiology is known to include drugs, infection, collagen tissue disease, and malignancy, but LCV caused by anti-tuberculosis drugs is very rarely seen. This report describes the case of a 12-year-old girl who developed LCV with rifampicin and ethambutol while undergoing anti-tuberculosis treatment due to extensive pulmonary involvement.

Keywords: anti-tuberculosis drug; ethambutol; leukocytoclastic vasculitis; rifampicin.

Publication types

  • Case Reports

MeSH terms

  • Antitubercular Agents / adverse effects*
  • Biopsy
  • Child
  • Female
  • Humans
  • Skin / pathology
  • Tuberculosis, Pulmonary / drug therapy
  • Vasculitis, Leukocytoclastic, Cutaneous / chemically induced*
  • Vasculitis, Leukocytoclastic, Cutaneous / diagnosis

Substances

  • Antitubercular Agents