GABA Deficits Enhance the Psychotomimetic Effects of Δ9-THC

Neuropsychopharmacology. 2015 Jul;40(8):2047-56. doi: 10.1038/npp.2015.58. Epub 2015 Mar 2.
No abstract available

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Brain Mapping
  • Dissociative Disorders / chemically induced*
  • Double-Blind Method
  • Dronabinol / blood
  • Dronabinol / pharmacology*
  • Electroencephalography
  • Event-Related Potentials, P300 / drug effects*
  • Flumazenil / administration & dosage
  • Flumazenil / analogs & derivatives
  • Humans
  • Male
  • Pain Measurement
  • Psychiatric Status Rating Scales
  • Psychotic Disorders / diagnosis
  • Psychotic Disorders / etiology*
  • Psychotic Disorders / physiopathology
  • Psychotropic Drugs / pharmacology*
  • Young Adult
  • gamma-Aminobutyric Acid / deficiency*

Substances

  • Psychotropic Drugs
  • Flumazenil
  • gamma-Aminobutyric Acid
  • iomazenil
  • Dronabinol