[A case of resection margin involvement gastric carcinoma that relapsed late after additional gastrectomy]

Gan To Kagaku Ryoho. 2014 Nov;41(12):2408-10.
[Article in Japanese]

Abstract

We report a case of a patient with resection margin involvement gastric carcinoma that recurred 5.5 years after additional resection. A 64-year-old man underwent distal gastrectomy for advanced gastric carcinoma (sig+por2, pSE, pN0, pStage IIB) in January 2008. A total gastrectomy was performed 2 months after the initial gastrectomy because of proximal resection line involvement, and curative resection was obtained. Adjuvant chemotherapy with S-1 was completed, and follow-up surveillance was finished 5 years after the additional surgery. In November 2013, the patient experienced bouts of vomiting, and a computed tomography (CT) scan showed an abdominal abscess that had spread to the liver and communicated with the intestine. Despite abscess drainage and antibiotic therapy, infection control was difficult and the patient died 20 days after hospitalization. An autopsy showed the recurrence lesions had diffusely spread to the peritoneum and was also disseminated around the Roux-Y jejunum. These findings suggest that peritoneal recurrence might lead to penetration of the intestine and abscess formation.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Abdominal Abscess / drug therapy
  • Abdominal Abscess / etiology
  • Anti-Bacterial Agents / therapeutic use
  • Antimetabolites, Antineoplastic / therapeutic use
  • Chemotherapy, Adjuvant
  • Drainage
  • Drug Combinations
  • Fatal Outcome
  • Gastrectomy
  • Humans
  • Male
  • Middle Aged
  • Oxonic Acid / therapeutic use
  • Recurrence
  • Stomach Neoplasms* / drug therapy
  • Stomach Neoplasms* / pathology
  • Tegafur / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Antimetabolites, Antineoplastic
  • Drug Combinations
  • S 1 (combination)
  • Tegafur
  • Oxonic Acid