BRAF(V600E) mutations are found in Richter syndrome and may allow targeted therapy in a subset of patients

Br J Haematol. 2015 Jul;170(2):282-5. doi: 10.1111/bjh.13291. Epub 2015 Mar 10.

¹ Department of Haematology, University College London Cancer Institute, London, UK.
² Institute of Pathology, University of Tubingen, Tubingen, Germany.
³ Department of Cellular Pathology, University College London, London, UK.
⁴ Haematopathology Unit, Department of Experimental Diagnostic and Specialty Medicine, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
⁵ Berlin Reference and Consultation Centre for Lymphoma and Haematopathology, Pathodiagnostik, Berlin, Germany.
⁶ Department of Cellular Pathology, University College London, London, UK. [email protected].

No abstract available

Keywords: BRAFV600E inhibitors; BRAFV600E mutations; chronic lymphocytic leukaemia; richter transformation; targeted therapy.

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