(18)F-Fluorine-18-l-dihydroxyphenylalanine ((18)F-DOPA) positive isolated peritoneal carcinomatosis from a MENII-related medullary thyroid carcinoma. About an atypical metastatic site and utility of (18)F-FDOPA

Anne-Laure Aziz; Lawrence Dierickx; Frederic Courbon; David Taïeb; Slimane Zerdoud

doi:10.1002/ccr3.159

(18)F-Fluorine-18-l-dihydroxyphenylalanine ((18)F-DOPA) positive isolated peritoneal carcinomatosis from a MENII-related medullary thyroid carcinoma. About an atypical metastatic site and utility of (18)F-FDOPA

Clin Case Rep. 2015 Feb;3(2):81-3. doi: 10.1002/ccr3.159. Epub 2014 Nov 24.

Authors

Anne-Laure Aziz¹, Lawrence Dierickx¹, Frederic Courbon¹, David Taïeb², Slimane Zerdoud¹

Affiliations

¹ Nuclear Medicine, Institut Claudius Regaud Toulouse, France.
² Nuclear Medicine, Assistance Publique-Hôpitaux de Marseille Marseille, France.

Abstract

A patient, operated for a medullary thyroid carcinoma (MTC) with a positive RET mutation, showed several peritoneal nodes on a computed tomography (CT), with increased Thyrocalcitonine. A (18)F-Fluorine-18-l-dihydroxyphenylalanine (18-F-FDOPA) positron emission tomography (PET/CT) showed isolated tracer uptake on the nodes. A biopsy confirmed that it was from the MTC, with the same RET mutation as in blood.

Keywords: 18F-DOPA (18F-Fluorine-18-l-dihydroxyphenylalanine); medullary thyroid carcinoma; multiple endocrine neoplasia; peritoneal carcinomatosis.

Publication types

Case Reports