Update on immunotherapy in melanoma

Surg Oncol Clin N Am. 2015 Apr;24(2):337-46. doi: 10.1016/j.soc.2014.12.010. Epub 2015 Jan 22.

Abstract

Immunotherapy is now recognized as a viable option for patients with metastatic melanoma. The field of immunotherapy now offers treatments with the potential for a long-term cure. As the field moves forward, studies will focus on improving the response rates with new immunotherapy agents or novel treatment combinations.

Keywords: Adaptive immunity; Antitumor immunity; Costimulatory blockade; Immunotherapy; Innate immunity; Metastatic melanoma.

Publication types

  • Review

MeSH terms

  • Antibodies, Monoclonal / therapeutic use
  • Antineoplastic Agents / therapeutic use
  • CTLA-4 Antigen / immunology
  • Humans
  • Immunotherapy*
  • Melanoma / immunology
  • Melanoma / therapy*
  • Skin Neoplasms / immunology
  • Skin Neoplasms / therapy*

Substances

  • Antibodies, Monoclonal
  • Antineoplastic Agents
  • CTLA-4 Antigen