Diagnosis of Cushing's disease

Pituitary. 2015 Apr;18(2):206-10. doi: 10.1007/s11102-015-0649-2.

Abstract

Diagnosis of Cushing's disease frequently remains a challenge. In this review we critically appraise the clinical features, biochemical tests, and imaging modalities used for this purpose. We outline recommendations for approaches to clinical investigation, with a particular focus on developments made within the last two years.

Publication types

  • Review

MeSH terms

  • ACTH-Secreting Pituitary Adenoma / blood
  • ACTH-Secreting Pituitary Adenoma / complications
  • ACTH-Secreting Pituitary Adenoma / diagnosis*
  • Adenoma / blood
  • Adenoma / complications
  • Adenoma / diagnosis*
  • Adrenal Cortex Function Tests*
  • Adrenocorticotropic Hormone / blood
  • Biomarkers / blood
  • Diagnostic Imaging* / methods
  • Humans
  • Hydrocortisone / blood
  • Pituitary ACTH Hypersecretion / blood
  • Pituitary ACTH Hypersecretion / diagnosis*
  • Predictive Value of Tests
  • Prognosis
  • Severity of Illness Index

Substances

  • Biomarkers
  • Adrenocorticotropic Hormone
  • Hydrocortisone