A new HLA-B allele, B*49:34, sequenced in a Spanish individual

Tissue Antigens. 2015 Apr;85(4):293-4. doi: 10.1111/tan.12546.

Abstract

HLA-B*49:34 shows one nucleotide difference regarding B*49:01:01 at codon 66 (ATC>GTC, I66>V66).

Keywords: B*49:34; human leukocyte antigen class I; new allele.

MeSH terms

  • Alleles*
  • Amino Acid Sequence
  • Amino Acid Substitution
  • Blood Donors
  • Exons
  • Genotype
  • HLA-B Antigens / genetics*
  • HLA-B Antigens / immunology
  • Histocompatibility Testing
  • Humans
  • Molecular Sequence Data
  • Platelet Transfusion
  • Point Mutation*
  • Polymerase Chain Reaction
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Spain
  • White People

Substances

  • HLA-B Antigens
  • HLA-B*49 antigen