Draft genome sequence of Acinetobacter sp. neg1 capable of degrading ochratoxin A

FEMS Microbiol Lett. 2015 Apr;362(7):fnv004. doi: 10.1093/femsle/fnv004. Epub 2015 Jan 18.

Abstract

Ochratoxin A (OTA) is a nephrotoxic and potentially carcinogenic mycotoxin produced by several species of Aspergillus and Penicillium. It is one of the major mycotoxins contaminating grain, grapes and a variety of food products, and the development of methods for reducing pre- and post-harvest contamination has drawn considerable attention. In the current study, we isolated and sequenced the genome of a novel free-living Acinetobacter strain able to degrade OTA. Biochemical studies suggest that the degradation reaction proceeds via peptide bond hydrolysis.

Keywords: Acinetobacter; degradation; ochratoxin A.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter / genetics*
  • Acinetobacter / metabolism
  • Base Sequence
  • Food Microbiology
  • Genome, Bacterial*
  • Hydrolysis
  • Molecular Sequence Data
  • Ochratoxins / metabolism*
  • Phylogeny
  • Sequence Analysis, DNA

Substances

  • Ochratoxins
  • ochratoxin A

Associated data

  • GENBANK/JSZD01000000