Normal values of spleen stiffness in healthy children assessed by acoustic radiation force impulse imaging (ARFI): comparison between two ultrasound transducers

Pediatr Radiol. 2015 Aug;45(9):1316-22. doi: 10.1007/s00247-015-3306-z. Epub 2015 Mar 22.

Abstract

Background: Portal hypertension, a major complication of hepatic fibrosis, can affect the stiffness of the spleen.

Objective: To suggest normal values of spleen stiffness determined by acoustic radiation force impulse imaging in healthy children and to compare measurements using two different US probes.

Materials and methods: In a prospective study, 60 healthy children between 1 day and 14 years of age were assigned to four age groups with 15 children in each. Measurements were performed using two transducers (convex 4C1 and linear 9L4), and 10 measurements were obtained in each child, 5 with each probe.

Results: The mean splenic shear wave velocities were 2.17 m/s (SD 0.35, 95% CI 2.08-2.26) with the 4C1 probe and 2.15 m/s (SD 0.23, 95% CI 2.09-2.21) with the 9L4 probe (not significant).

Conclusion: We found normal values for spleen stiffness with no difference in the mean values obtained using two types of US transducers, but with higher variability using a convex compared to a linear transducer.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adolescent
  • Aging / physiology*
  • Child
  • Child, Preschool
  • Elastic Modulus / physiology*
  • Elasticity Imaging Techniques / instrumentation*
  • Elasticity Imaging Techniques / standards
  • Equipment Design
  • Equipment Failure Analysis
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Reference Values
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Shear Strength / physiology
  • Spain
  • Spleen / diagnostic imaging*
  • Spleen / physiology*
  • Stress, Mechanical
  • Transducers*