[Morphological assessment of predictive factors in adenocarcinoma of the colon]

Vopr Onkol. 2014;60(5):619-24.
[Article in Russian]

Abstract

Immunohistochemical investigation of 15 different markers in colon adenocarcinoma was carried out. Prognostic significance showed chemokine receptor CXCR4 and Ki-67. Predictive significance was revealed for thymidylate synthase (TS) and thymidine phosphorylase (TP).

Publication types

  • English Abstract

MeSH terms

  • Adenocarcinoma / chemistry
  • Adenocarcinoma / mortality
  • Adenocarcinoma / pathology*
  • Adult
  • Aged
  • Biomarkers, Tumor / analysis*
  • Colonic Neoplasms / chemistry
  • Colonic Neoplasms / mortality
  • Colonic Neoplasms / pathology*
  • Disease-Free Survival
  • Female
  • Humans
  • Immunohistochemistry
  • Ki-67 Antigen / analysis*
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Prognosis
  • Receptors, CXCR4 / analysis*
  • Risk Assessment
  • Risk Factors
  • Thymidine Phosphorylase / analysis*
  • Thymidylate Synthase / analysis*

Substances

  • Biomarkers, Tumor
  • CXCR4 protein, human
  • Ki-67 Antigen
  • Receptors, CXCR4
  • Thymidylate Synthase
  • Thymidine Phosphorylase