Abstract
Disseminated histoplasmosis is an invasive fungal infection documented in patients with impaired cellular immunity coming from endemic areas (America, Asia, Africa). We report two cases of disseminated histoplasmosis in AIDS patients paradigmatic of the multifaceted nature of the disease, which may be an expression either of an advanced state of immunosuppression or the immune reconstitution inflammatory syndrome (IRIS).
MeSH terms
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AIDS-Related Opportunistic Infections / diagnosis
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AIDS-Related Opportunistic Infections / drug therapy
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AIDS-Related Opportunistic Infections / etiology*
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Acquired Immunodeficiency Syndrome / complications*
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Adult
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Amphotericin B / therapeutic use
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Antifungal Agents / therapeutic use
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Brazil
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Deoxycholic Acid / therapeutic use
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Diagnosis, Differential
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Drug Combinations
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Female
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Hepatitis B, Chronic / complications
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Hepatitis D, Chronic / complications
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Histoplasmosis / diagnosis
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Histoplasmosis / drug therapy
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Histoplasmosis / etiology*
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Homosexuality, Male
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Humans
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Immunocompromised Host*
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Invasive Fungal Infections
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Italy
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Male
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Risk Factors
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Thailand
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Treatment Outcome
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Voriconazole / therapeutic use
Substances
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Antifungal Agents
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Drug Combinations
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Deoxycholic Acid
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Amphotericin B
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amphotericin B, deoxycholate drug combination
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Voriconazole