Virulence, persistence and dissemination of Mycoplasma bovis

Sibylle Bürki; Joachim Frey; Paola Pilo

doi:10.1016/j.vetmic.2015.02.024

Virulence, persistence and dissemination of Mycoplasma bovis

Vet Microbiol. 2015 Aug 31;179(1-2):15-22. doi: 10.1016/j.vetmic.2015.02.024. Epub 2015 Mar 2.

Authors

Sibylle Bürki¹, Joachim Frey², Paola Pilo³

Affiliations

¹ Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.
² Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
³ Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland. Electronic address: [email protected].

PMID: 25824130
DOI: 10.1016/j.vetmic.2015.02.024

Abstract

Bovine mycoplasmosis due to Mycoplasma bovis causes several important bovine diseases such as pneumonia, mastitis, arthritis, otitis, genital disorders or keratoconjunctivitis. Variable surface lipoproteins, adhesion, invasion of host cells, modulation of the host immune system, biofilm formation and the release of secondary metabolites like hydrogen peroxide, as well as synergistic infections with other bacterial or viral pathogens are among the more significantly studied characteristics of the bacterium. The aim of this review is to summarize the current knowledge regarding the virulence of M. bovis and additionally, factors contributing to the dissemination and persistence of this pathogen in the bovine host will be discussed.

Keywords: Dissemination; Mycoplasma bovis; Persistence; Virulence attributes.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Cattle
Cattle Diseases / microbiology*
Cattle Diseases / transmission
Mycoplasma Infections / microbiology
Mycoplasma Infections / transmission
Mycoplasma Infections / veterinary*
Mycoplasma bovis / immunology
Mycoplasma bovis / pathogenicity*
Virulence