Endothelial chromosome 13 deletion in congenital heart disease-associated pulmonary arterial hypertension dysregulates SMAD9 signaling

Am J Respir Crit Care Med. 2015 Apr 1;191(7):850-4. doi: 10.1164/rccm.201411-1985LE.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Chromosome Deletion*
  • Chromosomes, Human, Pair 13 / genetics*
  • Endothelium
  • Female
  • Genetic Predisposition to Disease
  • Heart Defects, Congenital / complications
  • Heart Defects, Congenital / genetics*
  • Humans
  • Hypertension, Pulmonary / genetics*
  • Signal Transduction / genetics*
  • Smad8 Protein / genetics*
  • Smad8 Protein / metabolism*
  • Young Adult

Substances

  • Smad8 Protein