Plasma 25-hydroxyvitamin D concentration in patients with hip fracture in Hong Kong

Gerontology. 1989;35(4):198-204. doi: 10.1159/000213023.

Abstract

The serum concentration of 25-hydroxyvitamin D level and plasma albumin-adjusted calcium, phosphate, and alkaline phosphatase levels were studied in 200 patients with hip fracture (age range 49-93 years) and 427 elderly subjects living in the community (age range 60-90 years). The mean serum 25-hydroxyvitamin D levels in controls were higher than in temperate countries, but the 25-hydroxyvitamin D concentration was significantly lower in the patients than the controls for all sex and age groups. There was little difference in albumin-adjusted calcium and alkaline phosphatase levels, but the phosphate level was higher in the patients than in the controls. None of the patients with a low 25-hydroxyvitamin D level had a blood picture suggestive of osteopathy resulting from vitamin D deficiency or frank osteomalacia. Hip fracture patients with a low 25-hydroxyvitamin D level were much less ambulant and went outdoors much less frequently than hip fracture patients with a normal vitamin D level. A low vitamin D level was a risk factor for hip fracture in Hong Kong Chinese, and may be prevented by frequent outdoor exposure.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aging / blood
  • Alkaline Phosphatase / blood
  • Australia
  • Calcium / blood
  • Female
  • Hip Fractures / blood*
  • Hong Kong
  • Humans
  • Hydroxycholecalciferols / blood*
  • Male
  • Middle Aged
  • Osteomalacia / metabolism
  • Phosphates / blood
  • Sex Factors
  • Vitamin D Deficiency / blood*

Substances

  • Hydroxycholecalciferols
  • Phosphates
  • Alkaline Phosphatase
  • Calcium