Recent literature has reported an apparent increase in the incidence of pediatric venous thromboembolism over the last 10 years. In our study, data were collected from all children (ages 0 to 18 y) with a thrombotic event between January 2000 and May 2012, to determine whether an increased incidence of thromboembolism (TE) was evident and to investigate mitigating factors in the development of the TE. A total of 134 patients were entered into the study, 42% under the age of 1 year. There was no conclusive evidence of an increased incidence in our population over the period of the study. Within our population the peripheral venous system was the most common location for TE followed by cerebral vascular accidents. A thrombophilic risk factor was found in 84% of the patients. In our study 4.5% of the children had a second event.