[Postoperative morbidities after modified posterior pelvic exenteration for ovarian cancer]

Gynecol Obstet Fertil. 2015 May;43(5):342-7. doi: 10.1016/j.gyobfe.2015.03.006. Epub 2015 Apr 18.
[Article in French]

Abstract

Objective: Complication and survival analysis of cytoreduction surgery with modified posterior pelvic exenteration in the surgical treatment of the ovarian malignant tumor.

Methods: A retrospective monocentric study between 2000 and 2013 in Rhone-Alpes cancer treatment center. One hundred and fifty-two patients with ovarian cancer and treated by surgery with modified posterior pelvic exenteration were included. Complication in the 30 days after surgery was analysed by the Clavien-Dindo classification.

Results: In our study, rate of global complication was 62.5% with a morbidity rate of grave complication of 7.9%. Our rate of complete resection was 82.2%. Three fistulas (2.2%) were found. On average, there was 6.6±1.8 (2-11) surgery gesture associated with Hudson resection during surgery. In univariate analysis, there was a statistic significant association between complication from the rank II of Clavien-Dindo classification and supraradical surgery, post-chemotherapy surgery, recurrent surgery, the resection of a diaphragmatic dome, and the partial gastric resection. This association was also observed with the number of surgical gesture associated with Hudson resection.

Conclusions: The main prognostic surgical factor in ovarian cancer is to obtain a no macroscopic residual disease. The modified posterior pelvic exenteration allowed to obtain it. Our study demonstrates a low rate of grave complication further to this type of surgery.

Keywords: Cancer de l’ovaire; Chirurgie radicale; Complication; Complications; Exentération pelvienne postérieure modifiée; Modified posterior pelvic exenteration; Optimal cytoreduction; Ovarian cancer.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma / pathology
  • Carcinoma / surgery*
  • Female
  • Humans
  • Middle Aged
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / surgery*
  • Pelvic Exenteration / adverse effects*
  • Pelvic Exenteration / methods
  • Postoperative Complications
  • Prognosis
  • Retrospective Studies
  • Young Adult