Acute treatment of blood pressure after ischemic stroke and intracerebral hemorrhage

J Dedrick Jordan; Kathryn A Morbitzer; Denise H Rhoney

doi:10.1016/j.ncl.2014.12.003

Acute treatment of blood pressure after ischemic stroke and intracerebral hemorrhage

Neurol Clin. 2015 May;33(2):361-80. doi: 10.1016/j.ncl.2014.12.003. Epub 2015 Mar 17.

Authors

J Dedrick Jordan¹, Kathryn A Morbitzer², Denise H Rhoney²

Affiliations

¹ Department of Neurology, University of North Carolina at Chapel Hill School of Medicine, 2118 Physician Office Building, Campus Box 7025, Chapel Hill, NC 27599, USA; Department of Neurosurgery, University of North Carolina at Chapel Hill School of Medicine, 2118 Physician Office Building, Campus Box 7025, Chapel Hill, NC 27599, USA. Electronic address: [email protected].
² Division of Practice Advancement and Clinical Education, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, 115 Beard Hall, Campus Box 7574, Chapel Hill, NC 27599, USA.

PMID: 25907911
DOI: 10.1016/j.ncl.2014.12.003

Abstract

Blood pressure elevation in the setting of acute ischemic stroke and intracerebral hemorrhage is common. Controversy exists as to the optimal management of elevated blood pressure in this patient population. This article reviews the available clinical data that guides acute blood pressure management and how this may affect clinical outcomes. Furthermore, it examines how these data have led to controversies in their clinical application.

Keywords: Acute ischemic stroke; Blood pressure; Cerebral edema; Hematoma expansion; Hemorrhagic conversion; Hypertension; Intracerebral hemorrhage.

Publication types

Review

MeSH terms

Antihypertensive Agents / therapeutic use*
Blood Pressure*
Cerebral Hemorrhage / therapy*
Humans
Stroke / therapy*

Substances

Antihypertensive Agents